You’re Probably Fasting Wrong — Dr. Jon Schoeff Explains Why | Ep. 179
What if most people who say they’re fasting… aren’t actually fasting at all?
In this episode of A Healthy Point of View, Sam Tejada sits down with surgeon and longevity physician Dr. Jon Schoeff for a deep dive into fasting, metabolic health, muscle, ketones, exercise, and the fundamentals that often get lost in the noise of modern biohacking.
Dr. Schoeff challenges the way intermittent fasting is commonly discussed, distinguishing time-restricted eating from the biological state he considers a true fast. He explains why he tracks endogenous ketone production, how glucose and insulin influence metabolic flexibility, and why the same fasting duration may produce very different metabolic responses between individuals.
The conversation explores how training, glycogen depletion, low-intensity movement, sauna, and refeeding may fit into a structured fasting strategy. Sam and Dr. Schoeff also discuss the balance between growth and repair, including mTOR and AMPK signaling, resistance training, muscle power, body composition, glucose management, and why metabolic health involves far more than simply avoiding carbohydrates.
They also tackle some of the biggest debates in longevity and functional medicine: keto diets, added sugar, seed oils, omega-3s, peptides, GLP-1 medications, metformin, tesamorelin, stem cells, plasma exchange, exosomes, expensive biohacks, and the risks of trying to optimize an unhealthy foundation.
Most importantly, Dr. Schoeff brings the conversation back to something remarkably simple: before chasing advanced therapies, build the basics.
From movement and resistance training to sleep, nutrition, metabolic health, and intentional recovery, this episode asks an important question: Are we making longevity more complicated—and expensive—than it needs to be?
Disclaimer: This podcast is for educational and informational purposes only and is not medical advice. Some protocols, medication uses, fasting strategies, supplements, peptides, and longevity therapies discussed reflect the guest’s clinical perspective or emerging research and may not be appropriate for everyone. Extended fasting and prescription therapies should be discussed with a qualified healthcare professional.
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- Dr. Jon Schoeff
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- Sam Tejada
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